Scrotal ulceration following all-trans retinoic acid therapy for acute promyelocytic leukemia
نویسندگان
چکیده
منابع مشابه
Acute Promyelocytic Leukemia: All-Trans-Retinoic Acid Era
Acute promyelocytic leukemia (APL) is highly curable with the combination of all retinoic acid (ATRA) and anthracycline based chemotherapy, but the percentage of early deaths remains high. In the present study, we report the clinical, immunophenotypi molecular characteristics and outcome of APL patients diagnosed and treated in various Hospitals of Greece and Cyprus. We describe the data of nin...
متن کاملMature neutrophils with Auer rods following treatment with all-trans retinoic acid for acute promyelocytic leukemia.
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 3 10 /mL) with 13% atypical promyelocytes, anemia (hemoglobin of 6.8 g/dL), and thrombocytopenia (41 000 per mL). The atypical promyelocytes were medium to large in size with frequent bilobed nuclei, fine chromatin, and abundant cytoplasmic granules with occasional Auer rods. She was diagnosed with acute...
متن کاملAll-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results.
Twenty-two patients with acute promyelocytic leukemia were treated with all-trans retinoic acid (RA, 45 mg/m2 per day) for 90 days. Of the 22, four patients were previously untreated, two were resistant after conventional chemotherapy, and 16 were in first (n = 11), second (n = 4), or third (n = 1) relapse. We observed 14 complete response, four transient responses, one failure, and three early...
متن کاملAll - Trans Retinoic Acid a s a Differentiation Therapy for Acute Promyelocytic Leukemia
Twenty-two patients with acute promyelocytic leukemia were treated with all-trans retinoic acid (RA, 45 mg/m2 per day) for 90 days. Of the 22, four patients were previously untreated, two were resistant after conventional chemotherapy, and 16 were in first (n = 11 1, second (n = 4). or third (n = 1) relapse. We observed 14 complete response, four transient responses, one failure, and three earl...
متن کاملMassive ascites associated with all-trans retinoic acid treatment in therapy-related acute promyelocytic leukemia.
A 77-year-old man who developed pancytopenia was administered granulocyte colony-stimulating factor (G-CSF) by another doctor, and referred to us for the evaluation of pancytopenia. He had hepatocellular carcinoma and was treated with transcatheter arterial chemoembolization (TACE) containg epirubicin (total dose: 300 mg over the last two years). Bone marrow aspiration smear demonstrated hyperc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Dermatology
سال: 2011
ISSN: 0019-5154
DOI: 10.4103/0019-5154.87156